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Comparative study of the effects of remimazolam and dexmedetomidine on recovery and cognitive function after thoracoscopic surgery

Comparative study of the effects of remimazolam and dexmedetomidine on recovery and cognitive function after thoracoscopic surgery

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200063878
Enrollment
Unknown
Registered
2022-09-19
Start date
2022-09-15
Completion date
Unknown
Last updated
2023-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung space-occupying

Interventions

Remimazolam group:Remazolam (Group R): Continuously pump Remazolam Toluenesulfonate 0.2mg/kg/h at the beginning of anesthesia until the end of surgery
Dexmedetomidine group:Dexmetomidine (Group Y): Continuous infusion of Dexmetomidine 0.4 at the beginning of anesthesia µ G/kg/h until the end of the surgery

Sponsors

The First Affiliated Hospital of Guangxi Medical
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Patients undergoing elective thoracoscopic surgery; 2.ASA grade I-II; 3.Age: 18-65 years old, male or female; 4.BMI 18-30kg/m2 5.Sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with obvious abnormalities of severe cardiopulmonary, liver and kidney systems; 2. Patients with cognitive dysfunction or mental symptoms before operation; 3. Patients with communication and communication disorders; 4. Long term drug, alcohol and psychotropic substance abusers; 5. There are experimental contraindications to the experimental drugs in this study; 6. patients who did not agree to participate in this study.

Design outcomes

Primary

MeasureTime frame
Ricker sedation agitation score;Steward score;Modified Aldrete score;Mini mental state examination;

Secondary

MeasureTime frame
Visual analog Assessment Scale;

Countries

China

Contacts

Public ContactChen Yanhua

The First Affiliated Hospital of Guangxi Medical University

402009694@qq.com13978858025

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026