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Clinical trial of glutamine on pyruvate oxidation disorder

Clinical trial of glutamine on pyruvate oxidation disorder

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200063864
Enrollment
Unknown
Registered
2022-09-19
Start date
2022-09-19
Completion date
Unknown
Last updated
2023-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pyruvate oxidation disorder

Interventions

treatment group:glutamine treatment

Sponsors

Beijing Children's Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 16 Years

Inclusion criteria

Inclusion criteria: 1) <16 years old 2) Mitochondrial patients with pyruvate oxidation disorder

Exclusion criteria

Exclusion criteria: 1)patients with hepatic and renal dysfunction 2)take part in other medicine and ketogenic diet clinical trial 3) take gultamine within 2 weeks before enrolling in the study 4) allergic to glutamine

Design outcomes

Primary

MeasureTime frame
clinical symptom;NPMDS;—

Secondary

MeasureTime frame
lactate;Brain MRI;glutamine in CSF;—

Countries

China

Contacts

Public ContactFang Fang
13910150389@163.com13370115051

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026