rectal cancer
Conditions
Interventions
TaMIS group:TaMIS group
Sponsors
Department of General Surgery, First Medical Center, Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Male and female patients aged between 18 and 80 years old; 2. Colonoscopy before nCRT treatment: The distance between the lower edge of the tumor and the anal edge is<=12cm, and pathological biopsy shows rectal adenocarcinoma; Combined with chest and abdominal CT, rectal MRI, and other examinations, the initial evaluation was<=cT1N0M0, and/or the initial evaluation was<=cT1-3N0M0. After nCRT, the clinical staging was re evaluated as<=ycT1N0M0 (cCR/ncCR); 3. ECOG<2; 4. Obtain informed consent from the patient.
Exclusion criteria
Exclusion criteria: 1. Rectal cancer is more than 12cm away from the anal margin, and there are perforation, bleeding, obstruction, etc. before neoadjuvant radiotherapy and chemotherapy; 2. Patients with a history of pelvic radiation therapy; 3. Pregnant women; 4. Patients with distant organ metastasis or peritoneal implantation at the time of diagnosis; 5. Patients with tumors in other parts of the colon, including the colon, at the time of diagnosis; 6. Other concurrent or metachronous malignant tumors diagnosed within 5 years after the diagnosis of rectal cancer. 7. Subjects who are deemed unsuitable for participation in this study due to other reasons by the researcher; 8. Patients who refuse to participate or do not accept random allocation; 9. Patients with incomplete clinical information; 10. Patients who cannot be followed up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 3-year Disease-free survival (DFS);3-year local recurrence (LR); | — |
Secondary
| Measure | Time frame |
|---|---|
| 3-year Overall survival (OS); | — |
Countries
China
Contacts
Public ContactChaojun Zhang
First Medical Center, Chinese PLA General Hospital
Outcome results
None listed