infertility
Conditions
Interventions
Group 1 :Add Cetrorelix
Group 2:Without cetrorelix
Sponsors
Peking University Shenzhen Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Subjects who voluntarily participate in this research, understand the research and can sign the informed consent; 2. Those who plan to carry out IVF or ICSI assisted pregnancy treatment and need COH; 3. Meet the 2011 Bologna diagnostic criteria for normal ovarian reserve; 4. Aged 20 to 40 years old; 5. Indications for in vitro fertilization-embryo transfer: pelvic tubal factors, unexplained infertility, and male infertility.
Exclusion criteria
Exclusion criteria: 1. Patients with endocrine or metabolic abnormalities, such as hyperprolactinemia, hyperthyroidism, hypothyroidism, hyperandrogenemia, adrenal hyperfunction, adrenal insufficiency, etc.; 2. Suffering from endometrial polyps, uterine fibroids (diameter >= 4 cm or affecting the endometrium), uterine malformations, intrauterine adhesions and other uterine factor diseases or ovarian cysts >= 3 cm, pelvic endometriosis stage III-IV or Patients with adnexal (hydrosalpinx, fallopian tube tumors, etc.); 3. HIV or syphilis positive patients; 4. Patients who cannot understand the purpose, methods, etc. of this clinical trial, and who do not comply with the research procedures; 5. Patients with alcoholism, smoking, and drug abuse habits; 6. History of allergy to recombinant human follicle-stimulating hormone or excipients of this drug; 7. Participated in any other clinical trials after registering for this study or participated in another clinical study 3 months before random selection in this study; 8. Patients with a history of ovarian, breast, uterine, hypothalamic or pituitary tumors; 9. Failure of more than three consecutive IVF/ICSI cycles in the past; 10. Clomiphene or gonadotropin therapy within 1 month before enrollment; 11. Those with known chromosomal abnormalities and judged by researchers to have clinical significance; 12. Those who need epididymis or testicular puncture to provide sperm.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cumulative pregnancy rate; | — |
Countries
China
Contacts
Public ContactZhang Chunhui
Peking University Shenzhen Hospital
Outcome results
None listed