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FMR combined with functional near-infrared spectroscopy to investigate the effect of manual digitorum sensory stimulationon brain network plasticity in stroke patients

FMR combined with functional near-infrared spectroscopy to investigate the effect of manual digitorum sensory stimulationon brain network plasticity in stroke patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200063792
Enrollment
Unknown
Registered
2022-09-16
Start date
2022-09-16
Completion date
Unknown
Last updated
2023-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Group 1 :Detection of fMRI and fNIRS
Group 2:Giving regular rehabilitation treatment
Group 3:Give regular rehabilitation treatment and MDSS treatment

Sponsors

The Second Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Healthy adults: (1) No history of neurological, mental or other major diseases; (2) All have a background in rehabilitation medicine education to ensure that motor imagery tasks can be performed smoothly; (3) Confirmed as right-handed or left-handed by the Edinburgh Handedness Inventory (the Edinburgh Handedness Inventory, Oldfield, 1971); 2. Patients with stroke and hemiplegia: (1) Cerebral hemorrhage or cerebral infarction on one side, confirmed by cranial CT and MRI, manifested as paralysis of the right limb; the course of the disease is 1-3 months; (2) Right flexor muscle spasm MAS >= grade 1; (3) Age between 40-70 years old; (4) There are no fractures in the upper limbs on both sides, and no skin damage; (5) Stable condition; (6) Hearing comprehension is normal, and he can cooperate to complete the test; (7) Participate voluntarily and sign the corresponding informed consent form.

Exclusion criteria

Exclusion criteria: 1. Healthy adults: (1) Inability to cooperate during near-infrared acquisition; (2) The self-assessment of motor imagery task execution using visual analog scale (visual analogue scale, VAS) is less than 70 mm; 2. Patients with stroke and hemiplegia: (1) Tissue damage and peripheral nerve damage in the upper limbs; (2) Factors such as contracture lead to limited passive movement of the finger joints on the affected side.

Design outcomes

Primary

MeasureTime frame
Modified Ashworth Myospasm Scale (MAS);Manual muscle strength testing (MMT);Fugl-Meyer assessment of overall hand and upper extremity function;Modified Barthel Index, MBI;root mean square value of surface electromyography;blood oxygen concentration;

Secondary

MeasureTime frame
Lateral Index;Functional Contribution Degree;Functional Connectivity;

Countries

China

Contacts

Public ContactYongfeng Hong

The Second Affiliated Hospital of Anhui Medical University

hy_feng@163.com+86 13966797286

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 5, 2026