Anesthesia for upper gastrointestinal endoscopy
Conditions
Interventions
Group 1 :Remazolam + 1.0 mg/kg lidocaine
Group 2:Remazolam + 0.5 mg/kg lidocaine
Group 4:Remazolam + normal saline group
Sponsors
Ya'an People's Hospital
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Select patients who receive painless gastroscopy; 2. Age >= 65 years old; 3. BMI 18-28 kg/m2 4. ASA classification I-II.
Exclusion criteria
Exclusion criteria: 1. Preoperative systolic blood pressure >= 180 mmhg; Diastolic pressure >= 110 mmhg; Heart rate >= 110 beats/min; 2. Allergy history of test drug; 3. History of nervous system diseases or inability to communicate normally; 4. Long-term history of taking sedative and analgesic drugs; 5. Patients and their families refused.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Remazolam ED50 and ED95; | — |
Secondary
| Measure | Time frame |
|---|---|
| Noninvasive blood pressure;Heart rate;Blood oxygen saturation;Time of recovery from anesthesia;dosage; | — |
Countries
China
Contacts
Public ContactZhou Shuzhi
Ya'an People's Hospital
Outcome results
None listed