Severe Fever with Thrombocytopenia Syndrome
Conditions
Interventions
Group 1 :oral ruxolitinib
Sponsors
Shandong University Qilu Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with SFTS: Diagnostic criteria for confirmed cases: patients with epidemiological history (history of working, living or traveling in hilly, forest or mountain areas during epidemic season, or history of tick bites within 2 weeks prior to onset), fever and other clinical manifestations, and decreased platelet and white blood cells in peripheral blood. PCR detection of novel Bunyavirus nucleic acid in case samples was positive; 2. Clinical score >= 8 points.
Exclusion criteria
Exclusion criteria: 1. Patients under the age of 18 years; 2. Patients who are pregnant or have a positive pregnancy test before the first administration; 3. Patients with a history of allergy to ruxolitinib.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Death or not; | — |
Secondary
| Measure | Time frame |
|---|---|
| length of hospital stay in ICU;length of hospital stay; | — |
Countries
China
Contacts
Public ContactSai Wen
Shandong University Qilu Hospital
Outcome results
None listed