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A prospective study of nutrition and exercise management in improving Sarcopenia in colorectal cancer patients undergoing chemotherapy

A prospective study of nutrition and exercise management in improving Sarcopenia in colorectal cancer patients undergoing chemotherapy

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200063757
Enrollment
Unknown
Registered
2022-09-15
Start date
2022-09-15
Completion date
Unknown
Last updated
2023-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

Experimental group:nutrition and exercise investigation and Intervention
Control Group:nutrition and exercise investigation

Sponsors

Ningbo Huamei Hospital, University of Chinese Academy of Sciences (Ningbo Second Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Adult patients aged 18 to 75 years, regardless of gender; 2. Patients who have undergone colorectal cancer surgery, are pathologically diagnosed as colorectal cancer, and plan to receive chemotherapy; 3. Patients with expected survival time >= 6 months; 4. Patients who can comply with themselves or their family members, are willing and able to use digital platforms for self-management, and are willing to communicate with project team staff on WeChat or by phone; 5. Sign the informed consent form voluntarily, and complete the questionnaire survey and follow-up visits as required; when unable to sign the informed consent form and complete the questionnaire survey and follow-up visits by themselves, legal representatives or guardians can act on their behalf.

Exclusion criteria

Exclusion criteria: 1. Patients with advanced malignant tumors of other systems or organs; 2. Patients who cannot tolerate chemotherapy due to physical conditions, or refuse chemotherapy; 3. Patients with any of the following conditions: (1) Renal dysfunction (BUN, Cr > 1.5 ULN or eGFR 2.5 ULN); (5) Severe cardiopulmonary dysfunction; (6) Neuropsychiatric diseases; (7) There are blood diseases, HIV and other conditions that are clinically considered inappropriate to participate in this study; 4. There are metal objects in the body (such as: internal fixation, pacemaker or stent, etc.) patients who cannot accept relevant tests or affect the test data; 5. Patients who are unable to take care of themselves and be active in life and eating (ADL score < 60 points); 6. After evaluation by nutritionists and doctors, patients who have eating contraindications (such as gastrointestinal bleeding, intestinal paralysis/obstruction, intestinal fistula, severe diarrhea, etc.), who cannot eat semi-liquid or receive enteral nutrition therapy; 7. Patients with contraindications to exercise intervention after evaluation by rehabilitation therapists; 8. Participating in other clinical researchers or other conditions that the researchers think are not suitable for participating in this study.

Design outcomes

Primary

MeasureTime frame
Skeletal muscle mass and strength;Nutrition assessment;physical examination;

Countries

China

Contacts

Public ContactHua Yu

Ningbo Huamei Hospital, University of Chinese Academy of Sciences (Ningbo Second Hospital)

148279603@qq.com+86 13867869182

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026