Correlation between colorectal polyps and intestinal bacterial overgrowth in metabolically related fatty liver disease

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200063755

Enrollment

Unknown

Registered

2022-09-15

Start date

2020-01-01

Completion date

Unknown

Last updated

2023-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

fatty liver disease and polyps

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. MAFLD diagnostic criteria are based on imaging (FibroScan) evidence of liver fat accumulation (hepatic steatosis), and one of the following three conditions: overweight/obesity, type 2 diabetes, metabolic dysfunction; 2. Perform electronic colonoscopy to confirm the existence of colorectal polyps and send them for pathological examination; 3. Perfect the methane hydrogen breath test.

Exclusion criteria

Exclusion criteria: 1. Previously diagnosed malignant tumors; 2. Patients diagnosed with organic intestinal diseases such as inflammatory bowel disease, colorectal melanosis, and familial polyposis; 3. Use of antibiotics, prebiotics and probiotics in the past 3 months; 4. Incomplete clinical data.

Design outcomes

Primary

Measure	Time frame
Tumor marker panel;Colonoscopy;	—

Secondary

Measure	Time frame
Blood chemistry;	—

Countries

China

Contacts

Public ContactHongju Yang

The First Alliliated Hospital of Kunming Medical Univesity

1379702184@qq.com+86 13888213607

Outcome results