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Effect of butorphanol tartrate nasal spray on uterine contraction pain and prolactin after cesarean section

Effect of butorphanol tartrate nasal spray on uterine contraction pain and prolactin after cesarean section

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200063746
Enrollment
Unknown
Registered
2022-09-15
Start date
2022-09-15
Completion date
Unknown
Last updated
2023-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

uterine pain

Interventions

experimental group:After delivery of the fetus, the puerpera was given butorphanol tartrate nasal spray 1 mg
control group:After delivery of the fetus, 0.1 ml of normal saline was given to the puerpera by nasal spray

Sponsors

General Hospital of the Western Theater of the Chinese People's Liberation Army
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Age > 18 and < 45 years; 2. Single pregnancy; 3. Planning to undergo cesarean section; 4. Combined spinal epidural anesthesia is planned; 5. Plan breastfeeding; 6. Sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Pregnancy-induced hypertension syndrome HELLP syndrome (hemolysis, elevated liver enzymes and low platelet count); hypertension, ischemic heart disease; long-term use of non-steroidal anti-inflammatory drugs (NSAIDs); 2. Addiction to alcohol, opioids, or sedative-hypnotics; mental disorder; 3. Have undergone any abdominal surgery before (except for cesarean section); have contraindications to spinal anesthesia; have contraindications to nasal administration (such as loss or lesion in the nasal cavity); 4. Suffering from hyperprolactinemia.

Design outcomes

Primary

MeasureTime frame
Uterine contraction pain;Prolactin;

Secondary

MeasureTime frame
Degree of sedation;first lactation time;nausea;vomit;respiratory depression;itchy skin;lethargy;dizziness;

Countries

China

Contacts

Public ContactGong Gu

General Hospital of the Western Theater of the Chinese People's Liberation Army

gonggu68@163.com+86 13980525688

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026