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Study on prediction and mechanism of post-stroke spasticity

Study on prediction and mechanism of post-stroke spasticity

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200063740
Enrollment
Unknown
Registered
2022-09-15
Start date
2022-09-15
Completion date
Unknown
Last updated
2023-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Group 1 :
Group 2:

Sponsors

Jing'an District Centre Hospital of Shanghai, Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. For the first time, it meets the diagnostic criteria of stroke in the 4th National Cerebrovascular Disease Conference in 1995, and is confirmed by head CT or MRI; 2. Age 18-100 years old; 3. Hemiplegia on one side of the limb; 4. Subjects have received standardized clinical assessment; 5. According to the investigator's judgment, the subjects must clearly understand the purpose of the research, and be willing and able to comply with the requirements to complete the entire study; 6. The subject has no history of brain injury, traumatic brain injury, stroke, intracranial tumor and other diseases of the central nervous system, or history of central nervous system surgery; 7. The subjects voluntarily participated in this study and signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Incomplete information; 2. The limbs under study have severe contractures or lesions that interfere with the research; 3. The subject has severe cognitive and/or communication impairments that can interfere with the research; 4. Phenol or alcohol block, plaster, and botulinum toxin were used to treat the spasticity of the patient's limbs within 1 year from the onset of stroke to the follow-up; 5. Women who are pregnant or breastfeeding; 6. Patients with serious primary diseases such as heart, liver, kidney, hematopoietic system and endocrine system, and mental illness.

Design outcomes

Primary

MeasureTime frame
Resistance to passive movement scale, REPAS;Site of cerebral infarction lesion;Size of cerebral infarct lesion;Alberta Stroke Program Early CT Score, ASPECTs;

Secondary

MeasureTime frame
NIH Stroke Scale, NIHSS;The UK Medical Research Council, MRC;Fugl-Meyer Assessment-Motor, FMA-M;Berg Balance Scale, BBS;Fugl-Meyer Assessment-Sense, FMA-S;Barthel Index, BI;Numerical Rating Scale, NRS;Modified Rankin Scale, mRS;

Countries

China

Contacts

Public ContactBei Wang

Jing'an District Centre Hospital of Shanghai, Fudan University

drwangbei@163.com+86 13564902663

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026