Chronic sleep disorders
Conditions
Interventions
Group 1 :placebo control
Group 2:tACS
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Chronic insomnia case group: outpatients/inpatients diagnosed with ICSD-3 chronic insomnia, aged 18-75 years, right-handed; 2. The diagnosis meets the diagnostic criteria of ICSD-3 Chronic Insomnia Disorder; 3. ISI >= 8 points; 4. Have not used physical therapy in the past 6 months, such as: MECT, rTMS, tES, acupuncture, etc.; 5. Have not used sedative hypnotics, antidepressants, antipsychotics, mood stabilizers or other drugs that can act on the central nervous system within at least 4 weeks of this episode; 6. Non-shift workers; 7. The total course of disease = 5 years.
Exclusion criteria
Exclusion criteria: 1. Persons with any mental disorder (MINI) at present or in the past; 2. Years of education < 5 years or IQ < 90 points; 3. Travelers across time zones within 3 months; 4. Have the habit of eating probiotics and prebiotic products; 5. Nervous system diseases, trauma-induced loss of consciousness, chronic physical diseases, brain organic diseases, and tumor patients; 6. There are currently other sleep disorders other than insomnia: PLMS, RLS, etc.; 7. Those who drank alcohol within 1 week before enrollment; 8. Drink coffee in the afternoon before the experiment; 9. Patients with clear contraindications of MRI and tACS.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| polysomnography;Insomnia Severity Index;Pittsburgh Sleep Quality Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment;Number Sign Conversion Quiz; | — |
Countries
China
Contacts
Public ContactYanyan Wang
West China Hospital of Sichuan University
Outcome results
None listed