FindTrial
Sign In

CASP1-/CASP11-mediated pyroptosis in the damage of blood-brain-barrier after large ischemic stroke

CASP1-/CASP11-mediated pyroptosis in the damage of blood-brain-barrier after large ischemic stroke

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200063727
Enrollment
Unknown
Registered
2022-09-15
Start date
2022-09-15
Completion date
Unknown
Last updated
2023-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

large ischaemic stroke

Interventions

None listed

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years old; 2. Admitted to hospital within 24 hours after the onset of focal neurological symptoms; 3. Meet the diagnostic criteria for acute cerebral infarction in the Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke in China 2018; 4. Meet the criteria for massive cerebral infarction: emergency head imaging examination shows that the ischemic area is >= 1/2 of the blood supply area of ??the middle cerebral artery; 5. The patient or legal representative signs the informed consent.

Exclusion criteria

Exclusion criteria: 1. Those who have not completed the emergency head imaging examination within 24 hours of onset; 2. Those who refuse or are unable to provide peripheral blood samples within 24 hours of onset.

Design outcomes

Primary

MeasureTime frame
malignant brain edema;—

Countries

China

Contacts

Public ContactSimiao Wu

West China Hospital of Sichuan University

simiao.wu@hotmail.com+86 18980606486

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026