medication overuse headache
Conditions
Interventions
Experimental group:Gastrodin
Control group:Placebo
Sponsors
Affiliated Hospital of Yunnan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Aged over 18 years old, suffering from primary headache, and meeting the diagnostic criteria for drug-overuse headache (code 8.2) in ICHD-3.
Exclusion criteria
Exclusion criteria: 1. Those who have received botulinum toxin A injection, nerve block therapy, and transcranial magnetic stimulation therapy within 4 months before the baseline collection; 2. Those who cannot complete the headache diary records during the baseline collection; 3. Women who are breast-feeding, pregnant, or preparing for pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| reduction in the mean number of monthly headache days from baseline at 24-week follow-up;proportion of cured medication overused headache at week-24; | — |
Secondary
| Measure | Time frame |
|---|---|
| headache intensity;proportion of cured medication overused headache;mean change from baseline in total HIT-6 score;50% responder rate;treatment failure;Quality of life;reduction in the mean number of monthly medication intake days from baseline for treatment failure;tolerability; | — |
Countries
China
Contacts
Public ContactFanyi Kong
Affiliated Hospital of Yunnan University
Outcome results
None listed