Pneumonia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged > 18 years old, clearly diagnosed with community-acquired pneumonia, and in line with the Chinese adult community-acquired pneumonia diagnosis and treatment guidelines (2016 edition) SCAP diagnostic criteria; 2. Endotracheal intubation is less than 24 hours; 3. Willing to send alveolar lavage fluid for mNGS testing at their own expense for the first time.
Exclusion criteria
Exclusion criteria: 1. Bronchiectasis; 2. Patients with active pulmonary tuberculosis; 3. Obstructive pneumonia; 4. There is a history of hospitalization 2 weeks before the onset of illness, and this infection cannot be excluded for hospital-acquired infections; 5. Patients who have been hospitalized or received mechanical ventilation for >= 2 days before enrollment; 6. Immunosuppressed hosts: including HIV-positive patients, agranulocytosis lasting more than 10 days, bone marrow stem cell transplantation, solid organ transplantation, recent glucocorticoid pulse therapy, immunosuppressant therapy, patients with solid tumors receiving radiotherapy and chemotherapy, etc.; 7. Patients who cannot understand and implement the investigation plan; 8. Bronchoscopy and lavage examination cannot be performed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pathogenic microbial species; | — |
Countries
China
Contacts
Xinqiao Hospital of Third Military Medical University