sinus node dysfunction
Conditions
Interventions
ischemic stroke:This study is an observational study and does not involve intervention.
Sponsors
The First Affiliated Hospital of Dalian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. From January 2011 to November 2021, diagnosed with sinus node dysfunction in the First Affiliated Hospital of Dalian Medical University, the First Affiliated Hospital of Jinzhou Medical University and Qilu Hospital of Shandong University (Qingdao); 2. Obtain the consent of the patient and sign the consent form for cardiac pacemaker implantation (if applicable), willing to accept the subject research, and complete the follow-up; 3. Patients with implanted cardiac pacemakers comply with the 2012 ACCF/AHA/HRS revised guidelines for permanent cardiac pacemaker implantation and anti-arrhythmic device treatment guidelines for Class I and Class IIa indications; 4. The case information is completely stored in the electronic medical record research database and can be viewed legally.
Exclusion criteria
Exclusion criteria: 1. Atrial fibrillation/atrial flutter (including atrial tachycardia or atrial high-frequency events) in the past or new (by electrocardiogram recording or cardiac implantable electronic device program-controlled recording); 2. The electrocardiogram data is missing; 3. Lack of P wave index: There is baseline drift in the ECG, obvious muscle tremor wave interference, and blurred images, which affect the P wave interpreter; there is sinus arrest but no sinus P wave; 4. Lost to follow-up; 5. Use of anticoagulants in patients with sinus node dysfunction; 6. Focal neurological deficits secondary to brain tumors, trauma, infection or other non-vascular causes; 7. There are other causes of atrial fibrillation that have not been effectively corrected, such as hyperthyroidism, heart valve disease or rheumatic heart disease, etc.; 8. Previous imaging examination [esophageal echocardiography and (or) pulmonary vein CT examination] confirmed the presence of thrombus in the left atrium or left atrial appendage.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| atrial fibrillation;ischemic stroke;P-wave indices; | — |
Secondary
| Measure | Time frame |
|---|---|
| left atrial diameter;left ventricular ejection fraction (LVEF);Blood glucose;low density lipoprotein-cholesterol;high density lipoprotein-cholesterol;estimated glomerular filtration rate;alanine aminotransferase; | — |
Countries
China
Contacts
Public ContactYunlong Xia
The First Affiliated Hospital of Dalian Medical University
Outcome results
None listed