Acute respiratory infections in children
Conditions
Interventions
Sponsors
Beijing Children's Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
1 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Age 1-12 years old,regardless of gender; 2. Children with acute respiratory tract infection accompanied by thick sputum and difficult sputum excretion (cough symptom score = 2 points during the day or at night); 3. Children who need expectorant treatment; 4. Those who have conditions to observe and record day by day. 5. Children between 1 and 8 years old, the informed consent should be signed by the guardian;Children between 8-12 years old,the informed consent should be signed by both the child and his/her guardian;
Exclusion criteria
Exclusion criteria: 1. Children diagnosed with severe pneumonia; 2. Children with cough duration =2 weeks; 3. Children with previous bronchial asthma and interstitial lung disease; 4. Children with previous other chronic respiratory diseases, such as primary ciliary dyskinesia and bronchiectasis; 5. Patients with previous systemic basic diseases of heart, brain, kidney, blood, immunity, endocrine.Such as congenital heart disease, epilepsy, hemophilia and autoimmune diseases, or children with congenital respiratory diseases and malnutrition; 6. Children with previous peptic ulcer; 7. Participated in other drug trials 3 months prior to inclusion; 8. Those who are known or suspected to be allergic to the ingredients of the drugs used in this study
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Disappearance time of main symptoms(wheezy phlegm ? wheezy sound in lung);Changes in quality of life scores before and after treatment;Compliance score;Incidence of adverse events; | — |
Primary
| Measure | Time frame |
|---|---|
| Changes of cough symptom scores before and after treatment; | — |
Countries
China
Contacts
Public ContactXu Baoping
Outcome results
None listed