persistent pulmonary hypertension of the newborn
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? Gestational age of 37 weeks = full-term neonates =42 weeks; The gestational age of preterm neonates = 28 weeks =37 weeks ?1500g= neonatal weight =4000g ? No perinatal asphyxia or hypoxia (1 min Apgar score >7 points) ? Informed consent has been obtained
Exclusion criteria
Exclusion criteria: ? Other laboratory or imaging findings suggested abnormalities, such as major cardiac structural abnormalities (Normal is defined as normal left and right ventricular size and functionnormal size of the left and right atria normal position of the internal diameters of the great arteries no valve stenosis or valve insufficiencyno coronary artery dilation and no atrioventricular septal defect). ? History of intrauterine growth restriction ? Maternal hypertension, gestational diabetes mellitus, hyperthyroidism, hypothyroidism, autoimmune disease or family history of cardiovascular disease during pregnancy ? Patent ductus arteriosus still existed at 28 days ? Intervention of pulmonary artery pressure was given in the neonatal period
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulmonary artery systolic pressure; | — |
Countries
China
Contacts
PEKING UNIVERSITY SHENZHEN HOSPITAL