Facial spasm
Conditions
Interventions
ciprofol group:Anesthesia and sedation were induced and maintained with cyclopofol.
propofol group:Anesthesia and sedation were induced and maintained with propofol
Sponsors
The First Affiliated Hospital of University of Science and Technology of China
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Unilateral disease, the first operation for hemifacial spasm; 2. Abnormal EMG response and facial nerve motor evoked potential were monitored by electrophysiological monitoring technique during operation; 3. Patients aged 18-70 years; 4. ASA classification II-III.
Exclusion criteria
Exclusion criteria: 1. Patients with secondary hemifacial spasm; 2. Patients with neuromuscular dysfunction; 3. Allergic to cyclopofol, propofol and other anesthetic drugs; 4. Abnormal liver and kidney function; 5. Long-term use of sedative and hypnotic drugs; 6. BMI over 30.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Amplitude changes of facial nerve motor evoked potentials during operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Success of intraoperative abnormal EMG response monitoring;Heart rate, mean arterial pressure, BIS value, cardiac function related indexes;Anesthesia time, operation time, recovery time, extubation time, anesthetic drug dosage;Intubation reaction, injection pain during induction period;Intraoperative unexpected body movement, spontaneous breathing recovery, intraoperative awareness;Restlessness, nausea and vomiting during the recovery period;Surgical outcomes and neurological complications; | — |
Countries
China
Contacts
Public ContactLi Juan
The First Affiliated Hospital of University of Science and Technology of China
Outcome results
None listed