Effect of lung protective ventilation on lung injury in patients undergoing spinal endoscopic surgery in prone position

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200063633

Enrollment

Unknown

Registered

2022-09-13

Start date

2022-09-01

Completion date

Unknown

Last updated

2023-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung damage

Interventions

Lung protective ventilation group:alveolar recruitment

Lung protective ventilation group:positive end expiratory pressure

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Age 55-75 years old; (2) Accept UBE surgery; (3) The expected mechanical ventilation time is more than 2 hours; (4) American Society of Anesthesiologists (ASA) grade = grade III.

Exclusion criteria

Exclusion criteria: (1) Combined with acute lung injury (ALI)/acute respiratory distress syndrome (ARDS); (2) Concurrent heart failure or suspected concomitant heart failure; (3) Received mechanical ventilation [including continuous positive airway pressure (CPAP)] within 15 days before surgery; (4) Combined with pneumothorax or bullae; (5) Combined with severe neurological dysfunction; (6) Moderate to severe hepatic and renal insufficiency; (7) Chronic obstructive pulmonary disease (COPD) requiring oxygen therapy or CPAP; (8) Participating in other clinical intervention trials.

Design outcomes

Primary

Measure	Time frame
Lung ultrasound score;Oxygenation Index;	—

Countries

China

Contacts

Public ContactLing Wang

shiyandouding@126.com15268820518

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026