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Effect of end-stage renal disease on the sedative effect of ciprofol

Effect of end-stage renal disease on the sedative effect of ciprofol

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200063628
Enrollment
Unknown
Registered
2022-09-13
Start date
2022-09-13
Completion date
Unknown
Last updated
2023-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

end-stage renal disease

Interventions

ESKD group:Ciprofol

Sponsors

The First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 64 Years

Inclusion criteria

Inclusion criteria: (1) ESKD group: Those who with end-stage renal disease underwent elective kidney transplantation for the first time; control group: Those who underwent elective general anesthesia with normal renal function; (2) Choose a supraglottic airway management tool such as the laryngeal mask; (3) The patient's age is 18-64 years old; (4) Body mass index is 18.5-24.0 kg/m2; (5) ASA classification I-III;

Exclusion criteria

Exclusion criteria: (1) The patients in the ESKD group had severe insufficiency of important organs except the kidneys, and the patients in the control group had severe insufficiency of important organs; (2) Patients who are allergic to anesthetics such as cyclopofol and propofol; (3) Long-term use of psychotropic drugs, severe cognitive and mental disorders; (4) Limited head and neck movement, Mallampati grade III or IV, mouth opening 24.0kg/m2; (6) Participate in other clinical investigators.

Design outcomes

Primary

MeasureTime frame
Ciprofol dosage;

Countries

China

Contacts

Public ContactLi Juan

The First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital)

huamuzi1999@126.com13956005465

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026