Skip to content

Prospective clinical randomized controlled trial on the safety and efficacy of novel coronavirus oral antiviral polypeptide LL-37 preparation

Prospective clinical randomized controlled trial on the safety and efficacy of novel coronavirus oral antiviral polypeptide LL-37 preparation

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200063622
Enrollment
Unknown
Registered
2022-09-13
Start date
2022-09-13
Completion date
Unknown
Last updated
2023-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

novel coronavirus pneumonia

Interventions

B:Lactococcus Lactis
A: antiviral polypeptide LL-37 preparation

Sponsors

Chinese PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) all patients with clearly diagnosed novel coronavirus pneumonia who voluntarily receive treatment and do not participate in other clinical trials; (2) aged >=18 years, approved by the ethics committee, fully understand and sign the informed consent.

Exclusion criteria

Exclusion criteria: (1) those who do not meet the above inclusion criteria; (2) pregnant and lactating women; (3) severe basic diseases of the liver (Child Pugh score >=C, AST > 5 times the upper limit); (4) serious renal damage basic diseases (estimated glomerular filtration rate <=30 ml/min / 1.73 m2, or is undergoing continuous renal replacement therapy, hemodialysis, peritoneal dialysis); (5) people who accepted any novel coronavirus pneumonia experimental treatment within 30days prior to evaluation; (6) people who are allergic to lactococcus lactis or pharmaceutical excipients.

Design outcomes

Primary

MeasureTime frame
nuclear acid test of the upper respiratory tract;CT test of lung;nuclear acid test of stool;

Countries

China

Contacts

Public Contactsun gang
sunok301@126.com13501078679

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026