Biliary Atresia
Conditions
Interventions
Trial group:Folic acid
Placebo:Placebo
Sponsors
Guangzhou Women and Children Medical Center
Eligibility
Sex/Gender
All
Age
No minimum to 0.3 Years
Inclusion criteria
Inclusion criteria: Patients diagnosed with BA and treated with Kasai procedure.The enrolled subjects should meet the following inclusion criteria: 1) Biliary atresia (BA) is definitely diagnosed by operation, and hepaticojejunostomy (Kasai procedure) is successfully conducted. 2) The age at operation is < 90 days 3) Parents or guardians sign informed consent.
Exclusion criteria
Exclusion criteria: Excluded subjects must meet one of the following exclusion criteria: 1)Anemia, epilepsy and other neurological diseases with unknown reasons; 2)Accompanied by severe deformities or infections and metabolic diseases; 3)Family members (especially the mother) have a history of folate allergy;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Survival time without cholangitis; | — |
Secondary
| Measure | Time frame |
|---|---|
| liver function index;ultrasound;Blood folate level;microelement; | — |
Countries
China
Contacts
Public ContactZhe Wen
Guangzhou Women and Children Medical Center
Outcome results
None listed