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Clinical randomized controlled study on the soft tissue augmentation with acellular dermal matrix and autologous soft tissue (DGG and CTG) around teeth

Clinical randomized controlled study on the soft tissue augmentation with acellular dermal matrix and autologous soft tissue (DGG and CTG) around teeth

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200063570
Enrollment
Unknown
Registered
2022-09-12
Start date
2022-09-15
Completion date
Unknown
Last updated
2023-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Soft tissue insufficient around teeth

Interventions

DGG group:Augmentation with DGG
CTG group:Augmentation with CTG

Sponsors

Nanjing Stomatological Hospital, Medical School of Nanjing University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: If any of the following is "no", the patient cannot accept the trial. (1) Aged >= 18 and <= 70 years, regardless of gender; (2) According to the diagnostic criteria of the 1999 International Classification of Periodontal Disease and the 2018 International New Classification of Periodontal and Peri-implant Diseases, the clinical diagnosis was Miller class I and class II gingival recession; (3) Periodontal probing depth=3mm; no loss of adjacent soft and hard tissue; plaque index was less than 20%.

Exclusion criteria

Exclusion criteria: If any of the following is "yes", the patient cannot accept the trial. (1) The patients who did not receive perfect periodontal basic treatment before operation; (2) Patients with infection at the treatment site; (3) Severe abnormal liver and kidney function; (4) Poor control of blood glucose (fasting blood glucose > 7.0 mmol / L); (5) Patients with uncontrolled and stable severe hypertension (systolic blood pressure >= 160 mmHg and / or diastolic blood pressure >= 100 mmHg); (6) Patients who need bone augmentation at the same time; (7) Smokers; (8) Pregnancy; (9) Coagulation disorders or taking anticoagulant drugs; (10) Other contraindications to oral and / or surgical treatment.

Design outcomes

Primary

MeasureTime frame
Complete Root Coverage;Mean Root Coverage;Keratinized Tissue Width;

Secondary

MeasureTime frame
Gingival Recession Depth;Probing Pocket Depth;Clinical Attachment Level;Gingival Thickness;Visual Analogue Scale;Patient acceptance;

Countries

China

Contacts

Public ContactBAOCHUN TAN
tanbaochun2002@163.com13701460015

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026