Gonorrhoea
Conditions
Interventions
Experimental group 1:Antibacterial spray A
Experimental group 2:Antibacterial spray B
Placebo group 1:Placebo spray
Placebo group 2:Placebo spray
Sponsors
Xi'an Jiaotong University Health Science Center
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Men who have sex with men in the past 3 months; (2) Men aged 18 years or above; (3) At baseline, men tested negative for Neisseria gonorrhoeae and Chlamydia trachomatis at oropharynx, urethra and anorectum; (4) Men co-infected with HIV, syphilis or other STIs are eligible.
Exclusion criteria
Exclusion criteria: (1) Unable to attend the scheduled visits because of travelling plan; (2) Current or long-term use of antibiotics; (3) Men with oral health problems who cannot tolerate lactic acid; (4) Not willing to use the spray within 18 weeks; (5) Men who know someone in their household who is currently enrolled in the study; (6) Currently participating in the other clinical trials.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Incidence of Neisseria gonorrhoeae infection at urethra or anorectum;Total incidence of Chlamydia trachomatis infection at any site;Incidence of Chlamydia trachomatis infection at oropharynx, urethra or anorectum;Incidence of syphilis infection;Adherence to the spray before and after sex;Adherence to the spray daily; | — |
Primary
| Measure | Time frame |
|---|---|
| Total incidence of Neisseria gonorrhoeae infection at any site;Incidence of Neisseria gonorrhoeae infection at oropharynx; | — |
Countries
China
Contacts
Public ContactLei Zhang
Xi'an Jiaotong University Health Science Center
Outcome results
None listed