glomerulonephritis
Conditions
Interventions
treatment group:Cotrimoxazole treatment
Sponsors
Xijing Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Obtain written informed consent; 2. Age: 18-80; 3. Patients diagnosed with glomerulonephritis (including primary and secondary glomerulonephritis) were treated with rituximab
Exclusion criteria
Exclusion criteria: (1) allergic to sulfamethoxazole and/or trimethoprim; (2) Evidence of active infection within 3 weeks prior to enrollment; (3) Antibiotics were used within 10 days before enrollment; (4) Other diseases: positive serological indicators of Hepatitis B Virus (HBV); Congenital or acquired immunodeficiency; Active infection or clinical evidence of active tuberculosis or active cytomegalovirus infection; A history of peptic ulcer and/or gastrointestinal bleeding; Granulocytopenia, thrombocytopenia; Malignant tumor; Congenital heart disease, arrhythmia, heart failure and other serious cardiovascular diseases; Severe mental illness; (5) Women of childbearing age have the following conditions: pregnancy, contraceptive failure, or lactation; Inability or unwillingness to use appropriate contraception
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| infection rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse events related to cotrimoxazole; | — |
Countries
china
Contacts
Public ContactLi-jie He
Xijing Hospital
Outcome results
None listed