acute kidney injury
Conditions
Interventions
case series:Nil
Sponsors
Department of Anesthesiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Patients who underwent non-cardiac surgery under general anesthesia in West China Hospital of Sichuan University from 2019.6.25 to 2021.12.31 (2) Age =18 years old (3) Patients who have both creatinine measurement results within 30 days before surgery and within 7 days after surgery
Exclusion criteria
Exclusion criteria: 1. Patients with definite neuropathy or psychosis, including dementia or seizures, a history of psychotropic substance abuse and inability to abstinence, or other substantial lesions that may increase CNS toxicity; 2. Participating in other clinical trials or participating in other clinical investigators 4 weeks before enrollment (except those not receiving treatment); 3. Systemic autoimmune disease or immune deficiency; 4. Refusing to collect blood samples; 5. Allergic to any drug in the protocol; 6. Pregnant and lactating women; 7. Major diseases that can cause test interference and uncontrolled active infected persons; 8. Primary or secondary central tumor; 9. Contraindications to chemotherapy; 10. Not considered suitable for inclusion. 11. Known active bacterial, viral, fungal, mycobacterial, parasitic, or other infections (other than nail bed skin fungal infections) or any major systemic infection event requiring intravenous antibiotic treatment or hospitalization (other than neoplastic fever) within 4 weeks prior to enrollment; 12. Application of other antitumor therapies (such as radiotherapy, chemotherapy, hormone therapy, biotherapy, immunotherapy); 13. Other serious medical conditions that may limit the subject's participation in the study, such as uncontrolled diabetes; Severe cardiac insufficiency (NYHA grade II or above); Acute coronary syndrome in the last 6 months; Coronary revascularization such as stenting, cabG, and other cardiac and macrovascular procedures within the last 6 months; Severe arrhythmias include frequent ventricular premature, ventricular tachycardia, rapid atrial fibrillation/flutter, and severe bradycardia. Uncontrolled hypertension: systolic blood pressure > 150 mmHg, diastolic blood pressure > 100 mmHg. Gastric ulcers (those identified by the investigators as being at risk for perforation); Active autoimmune diseases (e.g., systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, Sjogren's syndrome, autoimmune thrombocytopenia, etc.); Severe respiratory diseases (e.g. obstructive pulmonary disease and history of bronchospasm), etc.; 14. Hemophagocytic cell syndrome; 15. Hepatitis B surface antigen (HBsAg) or hepatitis B core antibody (HBcAb) was positive, and the peripheral blood hepatitis B virus (HBV) DNA titer was not within the normal reference range; Hepatitis C virus (HCV) antibody positive and HCV RNA positive in peripheral blood; Human immunodeficiency virus (HIV) antibody positive; Cytomegalovirus (CMV) DNA test positive; Who tested positive for syphilis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| minimal residual disease;Bone marrow flow cytometry; | — |
Countries
Chins
Contacts
Public ContactGuo Chen
Outcome results
None listed