stroke
Conditions
Interventions
TMS group:paired associative stimulation
sham group:sham paired associative stimulation
Sponsors
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: Part One: 1. Age >= 40 years old and 24. Part Two: 1. Onset of the first stroke; 2. Stroke recovery period, disease duration >= 6 months; 3. Age >= 40 years old and 24.
Exclusion criteria
Exclusion criteria: Part One: 1. The subjects had poor compliance and did not receive corresponding intervention according to the trial protocol; 2. The subjects refused to continue the subsequent intervention; 3. The subject quits voluntarily for unknown reasons; 4. After TMS intervention, the subject had TMS-related adverse events and refused to continue the treatment; 5. The subject has some comorbidities, complications, and special physiological changes, and is not suitable to continue to participate in this study; 6. The researcher considers it inappropriate to continue to participate in the study. Part Two: 1. There are contraindications of Mr, such as a pacemaker, a cardiac stent, claustrophobia, etc.; 2. There are contraindications to transcranial magnetic stimulation, such as cochlear implantation, history of epilepsy, metal implantation in vivo; 3. pregnant or lactating women; 4. non-right-handed hand; 5. Participated in or is participating in other clinical projects one month before enrollment; 6. Past month and current use of benzodiazepines, baclofen, and antidepressants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| functional reach test; | — |
Secondary
| Measure | Time frame |
|---|---|
| Berg Balance Scale;Modified Barthel Index,MBI;MRI;Technobody test;time-up and then go test; | — |
Countries
China
Contacts
Public ContactWu Jiajia
Yueyang Integrated Chinese and Western Medicine Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed