AIDS
Conditions
Interventions
Intervention group:Bicarbonate propionol tablets
Sponsors
Infectious of Department, Nanjing Second Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Meeting "the Diagnostic Criteria for HIV/AIDS Infection" (WS293-2019); 2. Aged >= 18 years; 3. Failure of previous treatment with the national free first-line ART regimen (sustained HIV RNA VL >= 200 copies/ml for 24 weeks, or >= 200 copies /ml again after reaching HIV RNA VL = 30 ml/min/1.73m2 (calculated by CKD-EPI formula).
Exclusion criteria
Exclusion criteria: 1. Integrase inhibitor resistance was previously identified; 2. Pregnant or lactating women; 3. The subject has other diseases and needs to take other drugs that interact with B/F/TAF, so B/F/TAF should be prohibited or the dosage should be adjusted, and the drug cannot be stopped; 4. Participating in other interventional clinical studies; 5. The person who is known to be allergic to the drug component; 6. Serious comorbidities or underlying diseases; 7. Suspected or confirmed history of alcohol and drug abuse; 8. Those who are not considered suitable to participate in the clinical trial by the investigator (e.g., weak, poor compliance, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CD4 Count;HIV RNA Viral Load; | — |
Countries
China
Contacts
Public ContactHu Zhiliang
Infectious of Department, Nanjing Second Hospital
Outcome results
None listed