schizophrenia
Conditions
Interventions
Case series:None
Sponsors
Peking University Sixth Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Including outpatient and inpatient patients; 2. According to the clinical examination of Axis I disorder (SCID-I/P) of the diagnostic and Statistical Manual of mental disorders, 4th Edition (DSM-IV-TR), it is consistent with schizophrenia; 3. Aged 18-45 years; 4. First onset schizophrenia; 5. Disease course <= 3 years; 6. Previous continuous medication <= 4 weeks, intermittent medication accumulation <= 12 weeks; 7. Able to understand the interview content and sign written informed consent.
Exclusion criteria
Exclusion criteria: 1. Have a history of major physical diseases in the past; 2. Past alcohol/drug dependence or abuse; 3. There are contraindications to second-generation antipsychotics such as olanzapine, risperidone, or aripiprazole; 4. Women who need to prepare for pregnancy or are already pregnant.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PANSS (Positive and Negative Syndrome Scale);IgG;Immune index;cognition test;PSP, Personal and Social Performance Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| attitudes towards drug-taking;adverse drug reaction;BRMS, Bech-Rafaelsen Mania Rating Scale;CDSS, Calgary Depression Scaler for Schizophrenia;ITAQ, Insight and Treatment Attitudes Questionnaires;Perceived Stress Scale-CV;Childhood Trauma Questionnaire, CTQ;CGI, Clinical Global Impression;MARS, Medication Adherence Rating Scale;UKU, Udvalg for Kliniske Undersogelser;PAS, pre-illness adaptability scale; | — |
Countries
China
Contacts
Public ContactXin Yu
Peking University Sixth Hospital
Outcome results
None listed