type 2 diabetes mellitus
Conditions
Interventions
Intervention group:drink fermented tangerine peel dark tea + receive diet and exercise counseling
control group:receive diet and exercise counseling
Sponsors
Guangzhou Red Cross Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosed with diabetes according to diagnostic criteria in Guideline for the prevention and treatment of type 2 diabetes mellitus in China (2020 edition); 2. Not abke to keep the blood sugar levels within the target range using dietary treatment with metformin: received metformin >= 1500 mg/day for at least 8 weeks, had hemoglobin A1c (HbA1c) of 7% to 9%and fasting blood glucose < 13.9 mmol/L; 3. Aged 18-70 years (included 18 and 70 years); 4. Signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Body mass index (BMI) 2.5 times the upper limit of normal value serum total bilirubin, serum creatinine, serum triglycerides >= 1.5 times the normal value, or Electrocardiogram (ECG), carotid B-ultrasound, cardiac B-ultrasound examination showed cardiovascular dysfunction; 3. Urinary microalbumin to creatinine ratio > 30 mg/g; 4. Severe diabetic ketoacidosis or severe infection; 5. Severe gastrointestinal disease; 6. Pregnancy or lactation; 7. History of tumor; 8. Severe peripheral neuropathy; 9. The investigator did not consider it appropriate to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| change of glycosylated hemoglobin from baseline; | — |
Secondary
| Measure | Time frame |
|---|---|
| sugar tolerance;insulin;attainment rate of glycosylated hemoglobin; | — |
Countries
China
Contacts
Public ContactRongshao Tan
Guangzhou Red Cross Hospital
Outcome results
None listed