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Effect of low-dose dexmedetomidine and dezocine on half effective amount of respiratory depression in patients with lumbar anesthesia induced by sufentanil

Effect of low-dose dexmedetomidine and dezocine on half effective amount of respiratory depression in patients with lumbar anesthesia induced by sufentanil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200063386
Enrollment
Unknown
Registered
2022-09-05
Start date
2022-09-05
Completion date
Unknown
Last updated
2023-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lower abdomen, pelvic sacral surgery

Interventions

dezocine group:dexmedetomidine and dezocine
no dezocine group:dexmedetomidine

Sponsors

Fuyang Hospital Of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients who are scheduled to undergo spinal anesthesia; 2. ASA grade I-II; 3. 18-60 years old; 4. BMI 18.5-27 kg/m2; 5. Take the test voluntarily and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. serious respiratory and circulatory diseases, such as severe coronary heart disease, copd, etc.; 2. combined with mental or endocrine system diseases; 3. a history of long-term use of psychiatric drugs or alcohol abuse; 4. Hemorrhagic disease or abnormal coagulation function; 5. History of allergy or adverse reaction to intraoperative drugs.

Design outcomes

Primary

MeasureTime frame
Half the effective dose of sufentanil for respiratory depression;—

Countries

China

Contacts

Public ContactXiaohui Zeng

Fuyang Hospital Of Anhui Medical University

41196798@qq.com+86 13866217071

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026