Dentition defect
Conditions
Interventions
experimental group:usage of collagen
control group:no usage of collagen
Sponsors
West China Hospital of Stomatology, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 18 and 60 (including 18 and 60), regardless of gender; 2. Absence or extraction of maxillary posterior teeth for at least three months; 3. The height of the remaining alveolar ridge at the deletion site ranged from about 3-6mm; 4. No contraindications of implant surgery for systemic diseases; 5. Subjects fully understand the benefits and risks of this trial and are willing to participate and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Cystic lesions in the maxillary sinus caused by root apical infection, maxillary sinus inflammation, and catheter blockage; 2. There are air-liquid planes, calcification images, and maxillary sinus-oral communication in the maxillary sinus; 3. The height of the remaining alveolar crest was less than 3mm; 4. Those with bad oral hygiene habits that cannot be corrected; 5. Patients with severely poor occlusal relationship or severe habitual bruxism; 6. Heart disease (i.e. grade II and above cardiac function disease); Abnormal liver and renal function (ALT, AST > 1.5 times normal; Patients with diabetes mellitus and poor blood glucose control (fasting blood glucose =8.0 mmol/L after control); 7. Uncontrolled metabolic diseases, such as diabetes, osteochondrosis, thyroid diseases, severe liver and kidney dysfunction; 8. Patients with bone diseases such as osteoporosis, osteomalacia and osteosclerosis; 9. Various bone defects caused by malignant tumors, active infectious diseases and metabolic bone diseases; 10. Body infection or acute infection at the surgical site; 11. Patients with aplastic anemia and other blood diseases, who have taken anticoagulant drugs in the past 3 months or whose blood coagulation test is not within the normal range; 12. The use of drugs that may affect the healing of hard and soft tissues, such as long-term use of sedative hypnotics (continuous use for more than 3 months), long-term use of non-steroidal anti-inflammatory drugs or adrenocorticosteroids (continuous use for more than 3 months), and ongoing or recent 3 months of drug treatment that may affect or promote bone metabolism; 13. Patients who have smoked heavily in the past 6 months and during bone healing (smoking more than 20 cigarettes/day); 14. Autoimmune diseases; 15. undergoing radiation therapy; 16. Mental illness, substance abuse, alcohol abuse; 17. The person is known to be allergic to the material used in the product; 18. Pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| RESIDUAL ALVEOLAR CREST HEIGHT;GRAFT VOLUME;HEIGHT GAIN; | — |
Countries
China
Contacts
Public ContactAnchun Mo
West China Hospital of Stomatology, Sichuan University
Outcome results
None listed