Helicobacter pylori infection
Conditions
Interventions
Togorasen combined medication group:Tigorazan combined with amoxicillin for treatment
Bismuth quadruple group:Tigorazen, bismuth potassium citrate, amoxicillin, clarithromycin tablets treatment
Sponsors
945th Hospital of the PLA Joint Logistic Support Force
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Age: 18-70 years old, male or female; 2. Positive urea breath test; 3. No previous H.pylori eradication treatment; 4. Patients or their legal representatives signed informed consent, understanding and agreeing to comply with the study requirements.
Exclusion criteria
Exclusion criteria: 1. The one had used PPI, potassium competitive acid blockers, antibiotics, H2 receptor antagonists, bismuth, probiotics and other drugs in the four weeks before treatment; 2. Pregnant or lactating women, patients with family planning during the study period; 3. During the treatment, non-steroidal anti-inflammatory drugs, adrenocorticosteroids, anticoagulants, alcohol abuse; 4. Patients allergic to the drugs used in the study; 5. There are other serious diseases affecting the evaluation of this study, such as severe liver disease, heart disease, kidney disease, malignant tumor, mental disease, etc.; 6. Patients with previous gastric and esophageal surgery; 7. Participated in other drug studies within the previous three months; 8. Difficulty in completing follow-up or other factors affecting compliance; 9. Failing to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 13C-urea breath test; | — |
Countries
China
Contacts
Public ContactRui Wang
945th Hospital of the PLA Joint Logistic Support Force
Outcome results
None listed