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Clinical study on the treatment of male infertility with Wuwei Fuzheng Yijing Decoction based on microplastics: study protocol for a Randomized Controlled Trial

Clinical study on the treatment of male infertility with Wuwei Fuzheng Yijing Decoction based on microplastics

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200063340
Enrollment
Unknown
Registered
2022-09-05
Start date
2022-09-01
Completion date
Unknown
Last updated
2023-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Male infertility

Interventions

Treatment group:Wuwei Fuzheng Yijing Decoction
Control group:Vitamin E Soft Capsules
Control group:Coenzyme Q10 Tablets

Sponsors

The First Affiliated Hospital of He'nan University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
25 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. couples of childbearing age, with normal sexual life and no contraceptive measures, the woman's reproductive capacity is normal, and the woman cannot conceive naturally within 1 year due to the man's factors; 2. DFI >= 30%; 3. men between the ages of 25-50; 4. Abstinence time is 2-7 days; 5. All patients did not take any infertility treatment drugs within one month before receiving treatment.

Exclusion criteria

Exclusion criteria: 1. Abnormal semen due to chromosomal factors; 2. Azoospermia; 3. Not abstinence within the specified time; 4. Abnormal semen parameters caused by reproductive tract infection or genitourinary system and other related diseases, such as varicocele ; 5. Those who take drugs that hinder spermatogenesis and sperm motility within three months, or those who receive radiotherapy and chemotherapy, have serious primary diseases, and are mentally ill; 6. Based on the researcher's perspective, subjects may have other clinical symptoms Experiments have an impact.

Design outcomes

Primary

MeasureTime frame
Semen microplastic content;Sperm DFI;Semen analysis (including sperm concentration, total sperm count, percentage of forward motility, total motility, etc.);

Secondary

MeasureTime frame
TCM Syndrome Score;

Countries

China

Contacts

Public ContactBaojun Ju
7743857@qq.com+86 18638141073

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026