Quality of recovery after lung surgery
Conditions
Interventions
Group1:Esketamine+ erector spinae plane block
Group2:Placebo+ erector spinae plane block
Group3:Esketamine+Intercostal nerve block
Group4:Placebo+Intercostal nerve block
Sponsors
The First Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years; 2. American Anesthesiologist Classification (ASA) I-III; 3. undergoing thoracoscopic pulmonary surgery under general anesthesia; 4. willing to participate in this study and provide written informed consent.
Exclusion criteria
Exclusion criteria: 1. Unplanned or emergency surgery; 2. Allergy to the drugs used in this study; 3. Severe cardiopulmonary disease (myocardial infarction, heart failure, type I or type II respiratory failure); 4. Severe cerebrovascular diseases (cerebral hemorrhage, stroke); 5. Severe liver and kidney diseases (Child-Pugh grade C, renal replacement therapy); 6. Severe neurological diseases (Parkinson's disease, Alzheimer's disease), use of antipsychotics, alcohol abuse, long-term use of opioids or other analgesics; 7. uncontrolled hypertension, increased intracranial pressure, high intraocular pressure (glaucoma), and penetrating ocular trauma; 8. Unable to understand postoperative recovery scale and pain rating scale; 9. BMI >= 35 kg/m2.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QoR-15 score; | — |
Secondary
| Measure | Time frame |
|---|---|
| QoR-15 score;VAS pain scores;fentanyl consumption;Use of rescue analgesics;hypotension;hypertension;bradycardia;tachycardia;use of vasopressors;use of atropine;PONV;use of antiemetics;adverse events (Respiratory depression, dizziness and mental side effects);severe complications (Pulmonary complications, cardiac complications, central nervous system complications, gastrointestinal complications, sepsis, postoperative bleeding, reoperation, death);Postoperative hospitalization days; | — |
Countries
China
Contacts
Public ContactPeng Ke
The First Affiliated Hospital of Soochow University
Outcome results
None listed