Pulmonary Embolism
Conditions
Interventions
loading dose group:initial 2-3 day's loading dose of warfarin combined with iW-PC dose prediction model
Sponsors
Shanghai Sixth People’s Hospital
Eligibility
Sex/Gender
Female
Age
21 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. No thrombotic disease before pregnancy; 2. Aged >18 years; 3. Pulmonary embolism was diagnosed by CTA; 4. The patient has never used warfarin and agrees to use warfarin this time; 5. No anticoagulant contraindications; 6. The patient is capable of attending scheduled follow-up visits; 7. The patient and her family members signed an informed consent.
Exclusion criteria
Exclusion criteria: 1. A history of stroke; 2. A history of warfarin allergy; 3. Persons with mental disorders; 4. Severe liver and kidney diseases; 5. Heparin induced thrombocytopenia; 6. International standard ratio of prothrombin time (INR)=1.4; 7. platelet count <100 x 10^9/L before treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the time of reaching the expected level of INR; | — |
Countries
China
Contacts
Public ContactWeifeng Huang
Shanghai Sixth People's Hospital
Outcome results
None listed