burn surgery
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 65; 2. American Anesthesiologist Classification (ASA) I-II; 3. Patients requiring endotracheal intubation and general anesthesia for elective surgery; 4. Body mass index (BMI) >= 18 and = 10 and = 95% while breathing air; Systolic blood pressure (SBP) >= 90mmHg and = 60mmHg and = 55 and <= 100 beats/min; 6. Be able to understand the process and methods of this research, and volunteer to participate in this research.
Exclusion criteria
Exclusion criteria: 1. Patients with contraindications to general anesthesia or with a history of anesthesia accidents; 2. Patients with known or suspected allergies or contraindications to cyclopofol injection excipients, benzodiazepines, opioids, muscle relaxants, etc.; 3. Patients with craniocerebral loss, intracranial hypertension, stroke, unstable angina pectoris, myocardial infarction; 4. Respiratory insufficiency, obstructive pulmonary disease, the presence of a difficult airway, or difficult endotracheal intubation (modified Mahalanobis score grade III or IV); 5. Uncontrolled diabetes or hypertension; 6. Severe hepatic and renal insufficiency; 7. History of alcoholism or drug dependence; 8. Abuse or long-term use of anesthetic, sedative and analgesic drugs; 9. Medical history of mental illness; 10. Those who have participated in any drug clinical trial within 1 month before screening; 11. pregnant and lactating women; Fertile women or men were unwilling to use contraception throughout the trial; Subjects with pregnancy plans within 1 month after the trial (including male subjects); 12. Considered by the investigator to be inappropriate for participation in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Successful induction of anesthesia; | — |
Countries
China
Contacts
Wuhan Third Hospital