Effect of perioperative pregabalin on postoperative fatigue in patients with non-small cell lung cancer: a prospective, randomized controlled trial

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200063306

Enrollment

Unknown

Registered

2022-09-04

Start date

2022-09-20

Completion date

Unknown

Last updated

2023-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-small cell lung cancer

Interventions

Qne:Pregabalin

Two:Blank placebo

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years old; 2. ASA is classified as I-III; 3. Patients who intend to undergo thoracoscopic pneumonectomy.

Exclusion criteria

Exclusion criteria: 1. Patients with known allergies / adverse reactions to pregabalin; 2. Gabapentin or pregabalin is used currently; 3. Patients with severe renal impairment; 4. People who need long-term fasting; 5. Recent history of surgery or radiotherapy and chemotherapy; 6. Previous history of chronic pain or daily use of analgesics; 7. Patients with cognitive impairment and history of epilepsy.

Design outcomes

Primary

Measure	Time frame
Identity-Consequence Fatigue Scale;	—

Secondary

Measure	Time frame
Identity-Consequence Fatigue Scale;VAS Scale;HDA Scale;Arsens Insomnia Scale;PSQI Score;	—

Countries

China

Contacts

Public ContactWei Cheng

Huai'an First People's Hospital

53974314@qq.com+86 18796205791

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026