chronic endometritis
Conditions
Interventions
Gold Standard:Endometrial histopathology and immunohistochemistry obtained by hysteroscopic surgery were used as the "gold standard" for the diagnosis of CE.
Index test:16S rRNA high-throughput sequencing was performed on the uterine microecological samples of hysteroscopy patients, and 3 to 5 specific bacteria most related to CE were screened out as targe
Sponsors
Peking University Shenzhen Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Plan to undergo IVF-ET or have a history of IVF-ET failure (>= 1 time); 2. Spontaneous abortion (>= 2 times); 3. Infertility; 4. Abnormal uterine bleeding and fertility requirements.
Exclusion criteria
Exclusion criteria: 1. Accompanied by acute and chronic infectious diseases, diabetes, cardiovascular diseases, autoimmune diseases, thyroid diseases and mental diseases; 2. Received contraceptive pills or steroid hormone therapy within six months and systemic antibiotics within three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity;Positive predictive value;Negative predictive value; | — |
Countries
China
Contacts
Public ContactQing Chen
Peking University Shenzhen Hospital
Outcome results
None listed