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The effect of epidural analgesia on gastric emptying rate in perinatal period

The effect of epidural analgesia on gastric emptying rate in perinatal period

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200063277
Enrollment
Unknown
Registered
2022-09-02
Start date
2022-09-01
Completion date
Unknown
Last updated
2023-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastric emptying rate in perinatal period

Interventions

Study group:Epidural analgesia
Control group:Pharmacological and non-pharmacological interventions

Sponsors

Department of Anesthesiology, Qionglai Center Medical Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Primiparas aged 20-40 years (including 20 and 40); 2. Late pregnancy women with a gestational age greater than 37 weeks; 3. There is no obvious abnormality on the previous prenatal examination, and it is a low-risk mother; 4. Join the study voluntarily, sign the informed consent, have good compliance, and be willing to cooperate with the follow-up.

Exclusion criteria

Exclusion criteria: 1. Patients who have previously been diagnosed with gastroparesis, have esophageal, duodenal, or stomach disorders, and have a history of gastrointestinal operations; 2. Patients treated with serotonin 3 (5-HT3) receptor antagonists and metoclopramide for nausea and vomiting; 3. Patients with contraindications to epidural analgesia were eliminated from the epidural analgesia group, such as uncertain coagulation function or the use of anticoagulant medications, paired with scoliosis, and infection at the puncture site; 4. Women experiencing multiple pregnancies; 5. Pregnant women with complete placenta previa, placenta uteri implantation and other high-risk pathological pregnancy; 6. Women who are allergic to local anesthetics; 7. Patients with diabetes and gestational hypertension; 8. Patients with gestational nausea and vomiting after 9 weeks of gestational age; 9. Obesity with a BMI greater than or equal to 35 kg/m2, with or without obstructive sleep apnea; 10. The patient refuses to engage in the study, or is already engaging in other clinical studies, or is unable to cooperate due to their mental state, or the researchers deem them unsuitable for clinical trials.

Design outcomes

Primary

MeasureTime frame
Gastric emptying rate in the first stage of labor;

Secondary

MeasureTime frame
gastric emptying rate throughout labor;visual pain score;Fundal height;abdominal circumference;Maternal height and weight;Fetal birth;fetal position;fetal presentation;Fetal Apgar Score;fetal weight;time of each labor;Ultrasound amniotic fluid score;The total dose of anesthetics used;Intraoperative blood loss;Intraoperative fluid intake and output;Postoperative blood gas analysis;Postoperative pulmonary complications;Gastric capacity assessment at each time point;

Countries

China

Contacts

Public ContactLiu Yongfeng

Department of Anesthesiology, Qionglai Center Medical Hospital

11308906@qq.com+86 18996008690

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026