sleep disorders
Conditions
Interventions
Experimental group:Tai Chi chuan combined with rTMS
Control group:Tai Chi chuan combined with sham rTMS
Sponsors
National-Local Joint Engineering Research Center of Rehabilitation Medicine Technology, Fujian University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
60 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 60-75 years; 2. Meet the diagnostic criteria for primary insomnia in the International Classification of Sleep Disorders, 3rd edition; 3. Pre-treatment Pittsburgh Sleep Quality Scale score > 6; 4. Overall cognitive function score 18 < MoCA <26; 5. No combined psychiatric disorders such as depression and anxiety and neurological disorders such as stroke, dementia, Parkinson's disease, chronic pain; 6. Not engaged in regular exercise (at least 20 minutes of regular exercise at least 3 times a week) in the last 3 months; 7. Right-handed; 8. Able to understand and cooperate, voluntarily participate and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. The Geriatric Depression Scale-15 (GDS-15) score >= 9; 2. Taking any antipsychotic medication within the past 1 month; 3. Uncontrolled hypertension (systolic blood pressure > 160 mmHg or diastolic blood pressure 11%); 5. Those who are unable to cooperate with the completion of tai chi training or rTMS program, such as those with motor dysfunction caused by neurological diseases), musculoskeletal system diseases, serious organ diseases and other contraindications to exercise; 6. Patients who are not suitable for MRI scanning, such as those with metal-like substances implanted in the body (e.g., metal dentures, pacemakers, etc.) and spatial claustrophobia; 7. Those who are unable to complete the index assessment, such as those with severe aphasia, visual and hearing impairment; 8. Patients who are participating in other research trials that affect the results of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chinese revised Wechsler adult memory scale;Pittsburgh Sleep Quality Scale (PSQI); | — |
Secondary
| Measure | Time frame |
|---|---|
| Fuzhou version of Montreal cognitive assessment scale;Epworth daytime Sleepiness Scale;Hamilton Anxiety Scale;Hamilton Depression Scale;Wearable flexible sensor chip;fMRI;electroencephalogram;functional near-infrared spectroscopy;Serum mass spectrometry neurotransmitter assay; | — |
Countries
China
Contacts
Public ContactZhizhen Liu
National-Local Joint Engineering Research Center of Rehabilitation Medicine Technology, Fujian University of Traditional Chinese Medicine
Outcome results
None listed