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Effect of dezocine on postoperative cognitive function in patients undergoing transurethral holmium laser resection of bladder tumors: a randomised perspective clinical trial

Effect of dezocine on postoperative cognitive function in patients undergoing transurethral holmium laser resection of bladder tumors: a randomised perspective clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200063259
Enrollment
Unknown
Registered
2022-09-02
Start date
2022-09-01
Completion date
Unknown
Last updated
2023-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bladder tumors

Interventions

D group:Dezocine
G Group:general anesthesia

Sponsors

The Second Hospital, Shandong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. All patients or family members signed informed consent; 2. Patients with bladder tumors; 3. Undergoing analgesia with dezocine; 4. ASA grade I-III; 5. Aged 60-85 years.

Exclusion criteria

Exclusion criteria: 1. Preoperative cognitive impairment; 2. History of severe hypertension or heart disease; 3. Liver and kidney dysfunction; 4. Blood system diseases and abnormal bleeding and coagulation; 5. BMI > 30 kg/m2; 6. Recent use of antidepressants, sedatives or analgesics; 7. Recent history of radiotherapy and chemotherapy; 8. Distant organ metastasis; 9. Failure to complete data collection.

Design outcomes

Primary

MeasureTime frame
Postoperative cognitive index scale (MMSE);—

Secondary

MeasureTime frame
Adverse reaction;—

Countries

China

Contacts

Public ContactChang Feng

The Second Hospital, Shandong University

fengchang180@163.com+86 17660085521

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026