Radiation induced lung injury
Conditions
Interventions
experience group:Concurrent radiotherapy and chemotherapy + traditional Chinese medicine
Sponsors
Sichuan Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients with stage II and III (International Association for the study of Lung Cancer TNM 8th Edition) who are confirmed by histopathology or cell pathology to have lung cancer and other chest tumors that are not suitable for surgery are pre treated with radical radiotherapy; 2. It has the indication of concurrent radiotherapy and chemotherapy, and it is the first time to receive radiotherapy, and has not received chemotherapy and surgery; 3. Karnofsky performance status (KPS) score >= 60 points; 4. No obvious chronic lung inflammation was confirmed by lung CT before radiotherapy; 5. Normal blood routine and liver and kidney functions; 6. Aged 18-70 years; 7. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Any antineoplastic drugs other than systemic antineoplastic therapy that the subjects have been stably used and any treatment that may have an effect on the control of pulmonary fibrosis; 2. The patient has suffered from severe lung disease and is unlikely to benefit from treatment; 3. Combined with clinically unstable or uncontrollable blood, cardiovascular, lung, liver, kidney, pancreas or endocrine diseases, infectious diseases and mental diseases; 4. In the process of this study, it has been planned to participate in another clinical study of experimental drugs or equipment; 5. Known or suspected allergy to any component of the self-made "chemical fiber soup"; 6. The researcher believes that the subjects are not suitable to participate in this clinical study due to any clinical or laboratory abnormalities or other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of radiation-induced lung injury;Severity of radiation-induced lung injury; | — |
Countries
China
Contacts
Public ContactYin Jun
Outcome results
None listed