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Effect of remidazolam combined with sevoflurane general anesthesia on postoperative cognitive function in elderly patients undergoing surgery

Effect of remidazolam combined with sevoflurane general anesthesia on postoperative cognitive function in elderly patients undergoing surgery

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200063246
Enrollment
Unknown
Registered
2022-09-02
Start date
2022-09-01
Completion date
Unknown
Last updated
2023-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Digestive tract tumor

Interventions

control group:propofol
observation group:rimazole

Sponsors

Yongchuan Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Included in class III and below according to ASA classification criteria; 2. Patients who have been clearly diagnosed as requiring elective radical resection of digestive tract tumors; 3. No cognitive and behavioral impairment; 4. Informed consent was obtained and the informed consent form was signed.

Exclusion criteria

Exclusion criteria: 1. Coagulation dysfunction; 2. With severe bradycardia; 3. There are serious organic diseases such as liver and kidney dysfunction; 4. Have taken sedative and / or analgesic drugs in recent half a year; 5. Overweight or obese (body mass index >= 28.0 kg/m2); 6. There was a history of allergy to the drugs used in this study; 7. With mental illness.

Design outcomes

Primary

MeasureTime frame
mean arterial pressure;heart rate;Residence time in resuscitation room;Eye opening time;Extubation time;Cognitive score;

Countries

China

Contacts

Public ContactJiang Wei

Yongchuan Hospital of Chongqing Medical University

jiangwei8389@qq.com+8618883898339

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026