Osteoarthritis of the knee
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years; 2. Patients undergoing elective total knee replacement; 3. American Society of Anesthesiologists (ASA) I-II; 4. No communication barriers, able to cooperate with intervention implementation and operation of patient-controlled analgesia equipment; 5. Participants should participate voluntarily and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with chronic pain; 2. Patients with contraindications of regional anesthesia (puncture site infection, trauma, etc.) or allergic to the anesthesia drugs to be used; 3. Coagulopathy (prothrombin time > 14.0s, partial thromboplastin time > 40s, platelet count 40U/L, creatinine level > 1.5 mg/dL); 5. Patients taking opioids for more than three weeks before surgery; 6. Body Mass Index (BMI) > 30 kg/m2.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative Visual Analogue Scale score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative 24h hydromrophone consumption;Postoperative 48h hydromrophone consumption;Quality of Recovery-15 scale;Quadriceps muscle strength score; | — |
Countries
China
Contacts
Taizhou Hospital Affiliated to Wenzhou Medical University