Thyroid cancer
Conditions
Interventions
Experimental group (microwave ablation group):Ultrasound-guided microwave ablation
Control group (surgery group):Open surgery
Sponsors
Shenzhen Second People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Inclusion criteria of experimental group: (1) Patients voluntarily join the study and sign the informed consent; (2) Aged 18-60 years, generally in good condition; (3) Patients who had undergone subtotal thyroidectomy had DTC confirmed by postoperative pathology; (4) According to 131I Guidelines for the Treatment of Differentiated Thyroid Cancer (2021 Edition), Chinese Society of Nuclear Medicine, the patient was evaluated to receive follow-up 131I nail clearing therapy; (5) Clinical palpation, ultrasound and other imaging examinations suggested excessive residual nail; (6) Do not want to have a second operation to remove excessive residual nail or direct high dose 131I nail clearing treatment; (7) Imaging showed no cervical lymph node metastasis; (8) The patient's medical history was complete. 2. Inclusion criteria of control group: (1) Patients in the control group were obtained by referring to and screening past cases in the medical record room of our hospital; (2) Patients who had undergone subtotal thyroidectomy had DTC confirmed by postoperative pathology; (3) Follow-up 131I treatment was required after evaluation; (4) Clinical palpation, ultrasound and other imaging examinations suggested excessive residual nail; (5) Imaging showed no cervical lymph node metastasis; (6) The patient had undergone a second surgical operation to remove the excess residual nail; (7) The patient's medical history was complete; (8) There were no significant differences in gender composition, age and course of disease between control group and experimental group (P>0.05), indicating comparability.
Exclusion criteria
Exclusion criteria: 1. Exclusion criteria of experimental group: (1) Pregnant patients and lactation; (2) Severe heart, liver and kidney dysfunction; (3) Severe coagulation dysfunction; (4) Dysfunction of the contralateral vocal cord of stump nail, and the patient's inability to cooperate with the ablation operation under local anesthesia (such as severe cough, asthma, hiccup, etc.). 2. Exclusion criteria for control group: (1) Pregnant patients and lactation; (2) Severe heart, liver and kidney dysfunction; (3) Severe coagulation dysfunction; (4) Contralateral vocal cord dysfunction of residual nail.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Thyroid stimulating hormone; | — |
Secondary
| Measure | Time frame |
|---|---|
| Complication rate;Thyroglobulin;Serum thyroid hormones; | — |
Countries
China
Contacts
Public ContactLiu Weizong
Outcome results
None listed