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A randomized, double-blind, placebo-controlled clinical trial of berberine in the treatment of hypertriglyceridemia

A randomized, double-blind, placebo-controlled clinical trial of berberine in the treatment of hypertriglyceridemia

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200063197
Enrollment
Unknown
Registered
2022-09-01
Start date
2022-09-01
Completion date
Unknown
Last updated
2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypertriglyceridemia

Interventions

control group:Placebo

Sponsors

Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-70 years; 2. Patients with primary dyslipidemia; 3. 1.7mmol/L<=TG<11.3mmol/L(1000mg/dl) ; 4. Those who have not taken lipid-lowering drugs in the past 1 month; 5. Can adhere to long-term medication; 6. The patient's informed consent and signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Recent (within 4 weeks) myocardial infarction, or stenting, or bypass surgery, or stroke; 2. Diabetes mellitus, nephrotic syndrome and renal insufficiency; 3. Hypothyroidism or poor control of other endocrine diseases; 4. Liver function is more than 2 times higher than the upper limit of normal value; 5. Patients with severe or active liver disease; 6. Those who have any other life-threatening or serious illness and cannot complete the 12-week treatment to the extent that it affects the evaluation results; 7. Patients with allergic constitution; 8. Pregnant or planning to become pregnant; 9. Patients with hemolytic anemia and glucose-6-phosphate dehydrogenase deficiency; 10. Other diseases or mental disorders that researchers believe may limit the evaluation of efficacy or follow-up of patients; 11. Patients who have participated in clinical trials of other drugs within the last 4 weeks.

Design outcomes

Primary

MeasureTime frame
Triglyceride;

Secondary

MeasureTime frame
Total cholesterol;Low density lipoprotein cholesterol;High density lipoprotein cholesterol;Fasting blood glucose;

Countries

China

Contacts

Public ContactWu Shengxian
wushx@sina.com+86 10 84015528

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026