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The Effect of Dexmedetomidine on Postoperative Myocardial Injury in Patients

The Effect of Dexmedetomidine on Postoperative Myocardial Injury in Patients with Video-assisted Thoracoscopic Surgery

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200063193
Enrollment
Unknown
Registered
2022-09-01
Start date
2022-09-01
Completion date
Unknown
Last updated
2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myocardial Injury

Interventions

Sponsors

Jiaxing First Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients undergoing endotracheal intubation operation under general anesthesia from September 2022 to December 2023; 2. Patients undergoing video-assisted thoracoscopic surgery or non-cardiac surgery in the First Hospital of Jiaxing; 3. Aged >=45 years, ASA grade I-III, anesthesia time >=1 hour; 4. The study has been reviewed and approved by the ethics committee of the hospital, and all included patients have signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Abnormal cardiac (including unstable ischemic heart disease, complete bundle branch block, severe bradycardia, prolonged QT interval, diseased sinus syndrome, atrioventricular block of grade 2 or above without device, heart failure, etc.), brain, lung, liver (liver Child-pugh grade C), kidney (serum creatinine >442umol/L) and coagulation function, patients with a history of myocardial infarction within the last 30 days; 2. Patients with a history of taking analgesic drugs for chronic pain, a history of taking psychiatric substances, and contraindications to non-steroidal anti-inflammatory drugs; 3. Patients allergic to local anesthetics, dexmedetomidine and general anesthesia drugs; 4. BMI > 30kg/m^2; 5. Patients and their families refused surgical anesthesia and were unable to complete the questionnaire.

Design outcomes

Primary

MeasureTime frame
Hypersensitive troponin T;

Countries

China

Contacts

Public ContactZhou Qinghe

Jiaxing First Hospital

jxxmxy@163.com+86 13732573379

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 6, 2026