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High-throughput sequencing-based analysis of the mechanism of serum miRNAs in patients with heart failure accompanied by depressive symptoms

High-throughput sequencing-based analysis of the mechanism of serum miRNAs in patients with heart failure accompanied by depressive symptoms

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200063190
Enrollment
Unknown
Registered
2022-09-01
Start date
2022-09-01
Completion date
Unknown
Last updated
2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

heart failure

Interventions

Heart failure with depressive symptoms group:None
Heart failure without depressive symptoms group:None

Sponsors

Changzhou First People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Heart failure with depressive symptoms group: (1) Aged >=18 years, no gender limit; (2) The patient had certain language expression and understanding ability, understood and voluntarily filled in the informed consent form, and cooperated with the completion of blood test and questionnaire filling; (3) Patients with chronic heart failure who met the diagnostic criteria of ''Chinese Guidelines for the Diagnosis and Treatment of Heart Failure 2018'' and whose PHQ-9 scale score was >=10. 2. Heart failure without depressive symptoms: (1) Aged >=18 years, no gender limit; (2) The patient had certain language expression and understanding ability, understood and voluntarily filled in the informed consent form, and cooperated with the completion of blood test and questionnaire filling; (3) Patients with chronic heart failure who met the diagnostic criteria of ''China Guidelines for the Diagnosis and Treatment of Heart Failure 2018'' and whose PHQ-9 scale score was less than 10 points.

Exclusion criteria

Exclusion criteria: 1. Patients with severe respiratory, digestive, endocrine, blood system diseases and severe liver and kidney function impairment; 2. Patients with cardiac electronic devices; 3. Pregnant and lactating patients; 4. Patients with tumors and other mental disorders; 5. Unable to cooperate for other reasons or poor compliance; 6. History of drug abuse.

Design outcomes

Primary

MeasureTime frame
miRNA;

Countries

China

Contacts

Public ContactYang Ling

Changzhou First People's Hospital

linda_yl@sina.com+86 13616110633

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026